Success rates and results of the icsi method

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Intracytoplasmic sperm injection (ICSI) is the most used method for in vitro fertilization (IVF) of women's eggs after having been extracted by follicular puncture. Today, about 90% of IVF treatments use this technique.

However, it should be noted that the conventional IVF technique also has pregnancy rates similar to ICSI. The probability of getting a pregnancy depends more on the age and quality of the eggs than on the method of fertilization.

Next you have an index with all the points that we are going to treat in this article.

Index

ICSI success rates and results

How can you measure the success of ICSI?

To measure the success of ICSI, several percentages can be considered, such as the gestation rate or the birth rate. In this case, the most important thing is to get the birth of a healthy child, since there are many pregnancies that do not come to term.

At present, the ICSI technique results in around 37% of embryo transfer pregnancies and the delivery rate is 25%. This means that a live newborn is achieved for every 4 embryonic transfers.

On the other hand, if we consider the age of the woman, the success rates of ICSI are very different. This is due to the exhaustion of the ovarian reserve of the woman and the deterioration of the quality of her eggs with the passage of time.



Factors that influence the outcome of ICSI

ICSI is the technique preferred by most embryologists because of the many advantages it offers over conventional IVF. However, there are some factors that can influence your percentage effectiveness:

  • Experience and ability of the specialist to do it
  • Optimal conditions in the laboratory and incubator
  • Quality of ova
  • Maturation of ova
  • Age and ovarian reserve of women
  • Mobility and morphology of spermatozoa
  • Chromosomal abnormalities in gametes
  • Problems associated with a woman's uterus, such as endometriosis or fibroids

Some specialists have different opinions about the results of ICSI and assert that IVF offers some advantages in older women, such as obtaining embryos with fewer chromosomal alterations.

Despite this, the ICSI results have shown over the years that children born with this technique have a genetic abnormality rate comparable to that recorded in the normal population.

In the next post are all the positive and negative aspects of both techniques: FIV or ICSI?

ICSI success rates

As we have said, the results of ICSI vary greatly if one takes into account the age of the woman. The Spanish Fertility Society (SEF) differentiates 3 age ranges to indicate success rates per cycle.

Percentage of pregnancies

If we consider positive pregnancy tests in each IVF cycle performed, the rates obtained are as follows:

  • Women

    Percentage of deliveries

    As for the birth of a healthy child, which is the purpose of all assisted reproduction treatment, the following rates are obtained:

    • Women

      User questions

      What is the success of ICSI in a first attempt?

      The success of a fertility treatment with ICSI depends on many factors, especially maternal age. A woman who does not have her ovarian reserve severely affected and can recover about 8 eggs in the cycle, has a pregnancy rate of 37% per embryo transfer and a delivery rate of 25% after a first attempt.

      What is the success of ICSI if the semen of a man with azoospermia is used?

      With a severe male factor such as azoospermia, it will be necessary to perform a testicular biopsy to obtain spermatozoa.

      The success of spermatic microinjection depends on the ability of the embryologist to select spermatozoa that are alive in the biopsy and, if possible, with mobility and good morphology. If these spermatozoids are found, the success rates are similar to those of a cycle with normal semen recovery. According to SEF statistics, the probability of childbirth per cycle is 22%.

      What is the success of ICSI with DGP?

      Preimplantation genetic diagnosis often affects the development of embryos, resulting in lower success rates. In this case, the probability of delivery per cycle with PGD is 14%.

      What is the success of ICSI in an ovodonation treatment?

      The success rate of ICSI with donor eggs is much higher than in previous cases. The advantage of ovodonation is that the success rate does not decrease with the age of the recipient patient, resulting in embryo transfer pregnancy rates of 54-59%.

      Recommended Reading

      The ovarian reserve indicates the number of eggs available to a woman at any given time. If you want to know how it affects fertility and how it can be measured, you can read on here: What is the ovarian reserve?

      The number of ova recovered after ovarian stimulation influences the success of ICSI. To find out the ideal number for the treatment, see How many eggs need to be obtained for IVF?

      If you want to know the indications that lead a couple to resort to the technique of ICSI, you can continue reading here: Indications of ICSI.

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