What is the macs technique?

-

In recent years, a new technique of sperm selection has appeared: the annexin V columns. It allows the separation of spermatozoa of better quality through the application of magnetic fields, which is why it is also known by the name of MACS (magnetic-activated cell sorting). In this article we will explain what it is based on and what clinical applications it has.

Below you have an index with all the points that we will discuss in this article.

Index

What is the MACS technique? - Improvements in sperm selection

Advantages and disadvantages

The main advantage of this technique is that it allows discarding apoptotic sperm, which may not be detected by conventional sperm selection methods. Therefore, it is possible to separate the best quality sperm early.

Several studies have confirmed that thanks to the MACS technique with annexin V, pregnancy rates are improved.

However, it must be borne in mind that when using the annexin columns, the concentration of the seminal sample decreases considerably, since in the final sample, only healthy sperm will be present. This means that the sample resulting from this procedure, in most cases, can only be used for ICSI, since the concentration is insufficient to perform an artificial insemination or a conventional in vitro fertilization (IVF).

Another drawback of this technique is that it is more expensive and laborious than traditional methods. Therefore, it is only advisable to use it in patients in whom it is indicated.

Questions from users

Comments

Post a Comment

Popular posts from this blog

Gonal-f pen: doses of 300, 450 and 900 - How does it apply?

-
Gonal-f is a hormonal drug used in assisted reproduction treatments to cause the development of multiple follicles in the ovary. It is composed of the follicle-stimulating hormone (FSH), a gonadotropin that acts in the menstrual cycle of women. There are several formats of Gonal-f in the market, but one of the best known is the one that is administered with a pen-type injector. Below you have an index with all the points that we will discuss in this article. Index 1. Composition and presentation 2. Mode of administration 3. Questions from users 3.1. How should the pen of Gonal-f be preserved? 3.2. What is the use of the Gonal-f pen? 3.3. What happens if I miss a day of giving the dose of Gonal-f? 4. Recommended reading 5. Bibliography 6. Authors and collaborators Questions from users surrogate pregnancy in Tenerife(Spain)
Read more

Fertility treatments in the couple: how to get pregnant?

-
Image
According to the latest report of the Spanish Fertility Society (SEF), in 2016 were carried out 138,553 cycles of in vitro fertilization (IVF) and 36,463 cycles of artificial insemination (AI), which resulted in a total of 37,503 babies born . This represents an increase of 8% in the use of assisted reproduction techniques with respect to the previous year, which shows that more and more couples need help to have the opportunity to become parents. After a year of sexual intercourse without achieving pregnancy, a couple is considered to have sterility problems, so it is advisable to start doing diagnostic tests and determine the most appropriate assisted reproduction treatment in each case, as we will discuss throughout this post. Below you have an index with all the points that we will discuss in this article. Index 1. Custom fertility treatments 2. Artificial insemination (AI) 3. In vitro fertilization (IVF) 3.1. ICSI 3.2. DGP 4. Questions from users 4.1. How muc...
Read more

What is the purpose of the ovitrelle in a fiv treatment?

-
Image
Ovitrelle is a drug that contains recombinant hCG used in assisted reproduction to stimulate ovulation and thus favor pregnancy in the treatments of artificial insemination and in vitro fertilization (IVF). Below you have an index with all the points that we will discuss in this article. Index What is the ovitrelle for in an IVF treatment? 1. Composition 2. Instructions for use 3. Indications and contraindications 4. Risks and adverse effects 5. Ovitrelle and pregnancy test 6. Questions from users 6.1. Is it normal to give ovitrelle after the transfer of the embryos? 6.2. Does the ovitrelle advance the rule? 6.3. Does alcohol consumption negatively affect the effect of ovitrelle? 6.4. What is the price of the ovitrelle ?, does it go into social security? 6.5. Should it be kept in a refrigerator or at room temperature? Composition The active principle of ovitrelle is choriogonadotropin alfa, also called recombinant hCG (human chorionic gonadotropin). The qual...
Read more