Weight of the pregnant woman: cause of abortion

Causes sputum abortion the excessive weight of the pregnant

Obesity has been identified as a risk factor for spontaneous abortion, although the mechanism is not entirely clear. The purpose of this study is to better understand the effect of obesity on pregnancy success by analyzing cytogenetic studies of miscarriages in women with normal and elevated body mass index (BMI).

A retrospective study was conducted with women under 40 years of age by demographic registry, body mass index, karyotype of abortive remains and polycystic ovarian syndrome, which aborted in the first trimester of pregnancy, between 1999 and 2008.

For the statistical analysis we used the t-Student and the chi-square (X & sup2) considering the p 25 - Obese: BMI> 30

Repeat abortators were defined as those who had three or more miscarriages of clinical pregnancy.

Statistics

The statistical analysis was carried out using the Statistical Package for the Social Sciences version 15. The t-Student was used and the chi-square test (X & sup2) considering the p35 years) that had abortions, obtained a higher rate of abortive chromosomal abnormalities than in that they were younger than 35 years old. (67.6% vs. 49.5% of abnormal karyotypes, respectively).

On the other hand, obese women were more prone to suffer an abortion of chromosomally normal embryos, compared to those with a normal BMI (52.9% versus 36.6% respectively).

59% of abortions studied had abnormal karyotypes. The autosomal trisomy, that of chromosome 16, was the most observed in the karyotypes analyzed. The one on chromosome 22 was also quite common. There were no differences regarding embryonic sex.

Discussion

It has been found that there is a greater number of karyotypes of normal abortive remains in women with overweight or obesity (BMI ? 25) and this shows that the body mass index of the patient is completely independent with respect to embryonic aneuploidies. Despite these results, more studies are needed to find out the impact of overweight and obesity on lifestyle, insulin resistance and polycystic ovarian syndrome.

Authors and collaborators

Laura Gil Aliaga Embryologist specialist in Reproductive Medicine Degree in Biology and Biochemistry from the Miguel Hernández University of Elche and the University of Alicante (UA). Master's Degree in Biology of Assisted Human Reproduction. Embryologist in clinic UR Vistahermosa (Alicante) More informationEmbriquelo specialist in Reproductive Medicine. Degree in Biology and Biochemistry from the Miguel Hernández University of Elche and the University of Alicante (UA). Master's Degree in Biology of Assisted Human Reproduction. Embryologist in clinic UR Vistahermosa (Alicante) Notice: The information published in Assisted Reproduction ORG is a general support and a medical knowledge base that should not be used to self-diagnose a health problem or replace the consultation with a licensed doctor or specialist. author_box {background-color: #ececec; padding: 20px 30px; font-size: 14px;} .author_name {font-size: 16px; font-weight: bold; margin-bottom: 10px;} .author_title {margin-bottom: 10px; font-weight: bold;} .author_text {margin-bottom: 10px;} .author_box_izq {display: inline-block; vertical-align: top; width: 15%;} .author_box_dcha {display: inline-block; vertical-align: top; width: 85%;}. Author_box_dcha_sep {margin: 0 0 10px 30px} .autor_box: not (: last-child) {margin-bottom: 20px} @media screen and (max-width: 470px) {.autor_box {font-size: 16px; padding: 20px;} .author_name {font-size: 18px;} .autor_box_izq {width: 20%;} .autor_box_dcha { width: 80%;} .autor_box_dcha_sep {margin: 0 0 10px 20px}}