Embryo transfer: how many embryos do you have to transfer?

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One of the most controversial topics in in vitro fertilization treatments (IVF, ICSI) is the choice of the number of embryos to be transferred. It has to be decided without compromising the chances of success and, at the same time, without running the risk of multiple pregnancy. Currently, the experts' recommendations coincide in trying to transfer only one embryo, whether it is fresh cycles, vitrified (frozen) embryos or ovodonation.

Below you have an index with all the points that we will discuss in this article.

Index

Embryo transfer: How many embryos do you have to transfer?

How to decide how many embryos to transfer?

In Spain, the number of embryos to be transferred is legally regulated by Law 14/2006 on Assisted Reproduction Techniques, which allows the transfer of up to 3 embryos.

Transferring more embryos is related to an increased chance of getting pregnant. However, it also increases the likelihood of a multiple pregnancy (twins or triplets), with the consequent risk that this type of pregnancy is for the mother and babies.

Advances in assisted reproduction techniques

A few years ago, the most common was to transfer two or even three embryos. Currently, the results of reproductive treatments have improved so much that three embryos are almost never transferred and the transfer of a single embryo is becoming more frequent.

This change is due to the improvements that have occurred in this field, such as:

  • The optimization of embryonic culture.
  • The time-lapse technique.
  • The optimization of embryonic vitrification (freezing).
  • The endometrial receptivity test (ERA test).
Advances in assisted reproduction

These advances allow to have more embryos of good quality to choose from, select them better and synchronize the day of the transfer with the one of greater endometrial receptivity.

All this has meant a very significant increase in implantation rates per embryo transferred, which implies an increase in the probability of getting a healthy child at home with the transfer of a single embryo.

Transfer of a single embryo

For all the reasons explained, currently, professionals of assisted reproduction have reached the consensus that the transfer of a single embryo of high quality should be made whenever possible.

In this way, we increase the chances of success by transfer, due to the good embryo quality, avoiding the risk of multiple gestation.

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